Methylglyoxal metabolism in trypanosomes and leishmania

Methylglyoxal is a toxic by-product of glycolysis and other metabolic pathways. In mammalian cells, the principal route for detoxification of this reactive metabolite is via the glutathione-dependent glyoxalase pathway forming d-lactate, involving lactoylglutathione lyase (GLO1; EC 4.4.1.5) and hydr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wyllie, Susan, Fairlamb, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107426/
https://www.ncbi.nlm.nih.gov/pubmed/21310261
http://dx.doi.org/10.1016/j.semcdb.2011.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107426/
https://www.ncbi.nlm.nih.gov/pubmed/21310261
http://dx.doi.org/10.1016/j.semcdb.2011.02.001

Ejemplares similares