The DNA Binding and Bending Activities of Truncated Tail-less HMGB1 protein are Differentially Affected by Lys-2 and Lys-81 Residues and Their Acetylation

The role of lysines 2 and 81 as target sites for acetylation in full-length HMGB1 and truncated tail-less protein, respectively, has been studied by mutation analysis for the abilities of these proteins to bind and bend DNA. The DNA bending ability of truncated tail-less HMGB1 containing Lys-2 mutat...

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Detalles Bibliográficos
Autores principales: Elenkov, Ivan, Pelovsky, Petar, Ugrinova, Iva, Takahashi, Masayuki, Pasheva, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107488/
https://www.ncbi.nlm.nih.gov/pubmed/21647302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107488/
https://www.ncbi.nlm.nih.gov/pubmed/21647302

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