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CD248 facilitates tumor growth via its cytoplasmic domain

BACKGROUND: Stromal fibroblasts participate in the development of a permissive environment for tumor growth, yet molecular pathways to therapeutically target fibroblasts are poorly defined. CD248, also known as endosialin or tumor endothelial marker 1 (TEM1), is a transmembrane glycoprotein expresse...

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Detalles Bibliográficos
Autores principales: Maia, Margarida, DeVriese, Astrid, Janssens, Tom, Moons, Michaël, Lories, Rik J, Tavernier, Jan, Conway, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107809/
https://www.ncbi.nlm.nih.gov/pubmed/21549007
http://dx.doi.org/10.1186/1471-2407-11-162