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Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome

A transgenic mouse model for conditional induction of long-term hibernation via myocardium-specific expression of a VEGF-sequestering soluble receptor allowed the dissection of the hibernation process into an initiation and a maintenance phase. The hypoxic initiation phase was characterized by peak...

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Detalles Bibliográficos
Autores principales: Mayr, Manuel, May, Dalit, Gordon, Oren, Madhu, Basetti, Gilon, Dan, Yin, Xiaoke, Xing, Qiuru, Drozdov, Ignat, Ainali, Chrysanthi, Tsoka, Sophia, Xu, Qingbo, Griffiths, John, Horrevoets, Anton, Keshet, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107937/
https://www.ncbi.nlm.nih.gov/pubmed/21354174
http://dx.doi.org/10.1016/j.yjmcc.2011.02.010