Evaluating Pharmacokinetic and Pharmacodynamic Interactions with Computational Models in Supporting Cumulative Risk Assessment

Simultaneous or sequential exposure to multiple chemicals may cause interactions in the pharmacokinetics (PK) and/or pharmacodynamics (PD) of the individual chemicals. Such interactions can cause modification of the internal or target dose/response of one chemical in the mixture by other chemical(s)...

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Detalles Bibliográficos
Autores principales: Tan, Yu-Mei, Clewell, Harvey, Campbell, Jerry, Andersen, Melvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108131/
https://www.ncbi.nlm.nih.gov/pubmed/21655141
http://dx.doi.org/10.3390/ijerph8051613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108131/
https://www.ncbi.nlm.nih.gov/pubmed/21655141
http://dx.doi.org/10.3390/ijerph8051613

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