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Down-regulation of promoter methylation level of CD4 gene after MDV infection in MD-susceptible chicken line

BACKGROUND: Marek’s disease virus (MDV) is an oncovirus that induces lymphoid tumors in susceptible chickens, and may affect the epigenetic stability of the CD4 gene. The purpose of this study was to find the effect of MDV infection on DNA methylation status of the CD4 gene differed between MD-resis...

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Detalles Bibliográficos
Autores principales: Luo, Juan, Yu, Ying, Zhang, Huanmin, Tian, Fei, Chang, Shuang, Cheng, Hans H, Song, Jiuzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108237/
https://www.ncbi.nlm.nih.gov/pubmed/21645322
http://dx.doi.org/10.1186/1753-6561-5-S4-S7