Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-κB Signaling Pathways

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in the United States, suggesting that novel strategies for the prevention and treatment of PDAC are urgently needed. K-ras mutations are observed in >90% of pancreatic cancer, suggesting its ro...

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Detalles Bibliográficos
Autores principales: Wang, Zhiwei, Banerjee, Sanjeev, Ahmad, Aamir, Li, Yiwei, Azmi, Asfar S., Gunn, Jason R., Kong, Dejuan, Bao, Bin, Ali, Shadan, Gao, Jiankun, Mohammad, Ramzi M., Miele, Lucio, Korc, Murray, Sarkar, Fazlul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108612/
https://www.ncbi.nlm.nih.gov/pubmed/21673986
http://dx.doi.org/10.1371/journal.pone.0020537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108612/
https://www.ncbi.nlm.nih.gov/pubmed/21673986
http://dx.doi.org/10.1371/journal.pone.0020537

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