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Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis

Sporadic colon cancer is caused predominantly by dietary factors. We have selected bile acids as a focus of this review since high levels of hydrophobic bile acids accompany a Western-style diet, and play a key role in colon carcinogenesis. We describe how bile acid-induced stresses cause cell death...

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Detalles Bibliográficos
Autores principales: Payne, Claire M, Bernstein, Carol, Dvorak, Katerina, Bernstein, Harris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108627/
https://www.ncbi.nlm.nih.gov/pubmed/21677822