Cargando…
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis
Sporadic colon cancer is caused predominantly by dietary factors. We have selected bile acids as a focus of this review since high levels of hydrophobic bile acids accompany a Western-style diet, and play a key role in colon carcinogenesis. We describe how bile acid-induced stresses cause cell death...
Autores principales: | Payne, Claire M, Bernstein, Carol, Dvorak, Katerina, Bernstein, Harris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108627/ https://www.ncbi.nlm.nih.gov/pubmed/21677822 |
Ejemplares similares
-
Deoxycholate, an Endogenous Cytotoxin/Genotoxin, Induces the Autophagic Stress-Survival Pathway: Implications for Colon Carcinogenesis
por: Payne, Claire M., et al.
Publicado: (2009) -
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis
por: Payne, Claire M, et al.
Publicado: (2011) -
Carcinogenicity of deoxycholate, a secondary bile acid
por: Bernstein, Carol, et al.
Publicado: (2011) -
Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis
por: Payne, Claire M, et al.
Publicado: (2011) -
Role of bile acids in colon carcinogenesis
por: Nguyen, Thi Thinh, et al.
Publicado: (2018)