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Safety and efficacy of entecavir for the treatment of chronic hepatitis B

Entecavir is a cyclopentyl deoxyguanosine analog that was approved for the treatment of the hepatitis B virus (HBV) in 2005. In Phase III trials, it showed potent HBV suppression with drops of 6- to 7-log copies/mL in HBV DNA at 1 year. In addition, rates of genotypic resistance in nucleos(t)ide-naï...

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Detalles Bibliográficos
Autor principal: Osborn, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108748/
https://www.ncbi.nlm.nih.gov/pubmed/21694909
http://dx.doi.org/10.2147/IDR.S4188