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Monitoring resistance of Plasmdium vivax: Point mutations in dihydrofolate reductase gene in isolates from Central China

BACKGROUND: Malaria still represents a significant public health problem in China, and the cases dramatically increased in Central China after 2001. Antifolate resistance in Plasmodium vivax is caused by point mutations in genes encoding dihydrofolate reductase (pvdhfr) and dihydropteroate synthase...

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Detalles Bibliográficos
Autores principales: Huang, Fang, Zhou, Shuisen, Zhang, Shaosen, Li, Weidong, Zhang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108914/
https://www.ncbi.nlm.nih.gov/pubmed/21586132
http://dx.doi.org/10.1186/1756-3305-4-80