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Monitoring resistance of Plasmdium vivax: Point mutations in dihydrofolate reductase gene in isolates from Central China
BACKGROUND: Malaria still represents a significant public health problem in China, and the cases dramatically increased in Central China after 2001. Antifolate resistance in Plasmodium vivax is caused by point mutations in genes encoding dihydrofolate reductase (pvdhfr) and dihydropteroate synthase...
Autores principales: | Huang, Fang, Zhou, Shuisen, Zhang, Shaosen, Li, Weidong, Zhang, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108914/ https://www.ncbi.nlm.nih.gov/pubmed/21586132 http://dx.doi.org/10.1186/1756-3305-4-80 |
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