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A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhFGF21) Modified with Polyethylene Glycol

As one of fibroblast growth factor (FGF) family members, FGF21 has been extensively investigated for its potential as a drug candidate to combat metabolic diseases. In the present study, recombinant human FGF21 (rhFGF21) was modified with polyethylene glycol (PEGylation) in order to increase its in...

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Detalles Bibliográficos
Autores principales: Huang, Zhifeng, Wang, Huiyan, Lu, Meifei, Sun, Chuanchuan, Wu, Xiaoping, Tan, Yi, Ye, Chaohui, Zhu, Guanghui, Wang, Xiaojie, Cai, Lu, Li, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108960/
https://www.ncbi.nlm.nih.gov/pubmed/21673953
http://dx.doi.org/10.1371/journal.pone.0020669