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Hepatitis C Virus NS3 Protein Can Activate the Notch-Signaling Pathway through Binding to a Transcription Factor, SRCAP

Persistent infections of hepatitis C virus (HCV) are known to be a major risk factor for causing hepatocellular carcinomas. Nonstructural protein 3 (NS3) of HCV has serine protease and RNA helicase domains, and is essential for the viral replication. Further, NS3 is also considered to be involved in...

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Detalles Bibliográficos
Autores principales: Iwai, Atsushi, Takegami, Tsutomu, Shiozaki, Takuya, Miyazaki, Tadaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108961/
https://www.ncbi.nlm.nih.gov/pubmed/21673954
http://dx.doi.org/10.1371/journal.pone.0020718