Deactivation of Signal Transducer and Activator of Transcription 3 Reverses Chemotherapeutics Resistance of Leukemia Cells via Down-Regulating P-gp

Multidrug resistance (MDR) caused by overexpression of p-glycoprotein is a major obstacle in chemotherapy of malignant cancer, which usually is characterized by constitutive activation of signal transducer and activator of transcription 3 (STAT3), but their relation between MDR and STAT3 remains unc...

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Detalles Bibliográficos
Autores principales: Zhang, Xulong, Xiao, Weihua, Wang, Lihua, Tian, Zhigang, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108986/
https://www.ncbi.nlm.nih.gov/pubmed/21677772
http://dx.doi.org/10.1371/journal.pone.0020965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108986/
https://www.ncbi.nlm.nih.gov/pubmed/21677772
http://dx.doi.org/10.1371/journal.pone.0020965

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