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Trypanosomatid RACK1 Orthologs Show Functional Differences Associated with Translation Despite Similar Roles in Leishmania Pathogenesis

RACK1 proteins belong to the eukaryote WD40-repeat protein family and function as spatial regulators of multiple cellular events, including signaling pathways, the cell cycle and translation. For this latter role, structural and genetic studies indicate that RACK1 associates with the ribosome throug...

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Detalles Bibliográficos
Autores principales: Choudhury, Kohelia, Cardenas, Daviel, Pullikuth, Ashok K., Catling, Andrew D., Aiyar, Ashok, Kelly, Ben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108995/
https://www.ncbi.nlm.nih.gov/pubmed/21677780
http://dx.doi.org/10.1371/journal.pone.0020710