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Negative Regulation of Interferon-β Gene Expression during Acute and Persistent Virus Infections
The production of type I interferons (IFNs) in response to viral infections is critical for antiviral immunity. However, IFN production is transient, and continued expression can lead to inflammatory or autoimmune diseases. Thus, understanding the mechanisms underlying the negative regulation of IFN...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108996/ https://www.ncbi.nlm.nih.gov/pubmed/21677781 http://dx.doi.org/10.1371/journal.pone.0020681 |