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Negative Regulation of Interferon-β Gene Expression during Acute and Persistent Virus Infections

The production of type I interferons (IFNs) in response to viral infections is critical for antiviral immunity. However, IFN production is transient, and continued expression can lead to inflammatory or autoimmune diseases. Thus, understanding the mechanisms underlying the negative regulation of IFN...

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Detalles Bibliográficos
Autores principales: Ye, Junqiang, Maniatis, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108996/
https://www.ncbi.nlm.nih.gov/pubmed/21677781
http://dx.doi.org/10.1371/journal.pone.0020681