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Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin–β-catenin

Frizzled/planar cell polarity (PCP) signaling regulates cell motility in several tissues, including ommatidial rotation in Drosophila melanogaster. The Nemo kinase has also been linked to cell motility regulation and ommatidial rotation. The mechanistic role(s) of Nemo during rotation remain however...

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Detalles Bibliográficos
Autores principales: Mirkovic, Ivana, Gault, William J., Rahnama, Maryam, Jenny, Andreas, Gaengel, Konstantin, Bessette, Darrell, Gottardi, Cara J., Verheyen, Esther M., Mlodzik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109122/
https://www.ncbi.nlm.nih.gov/pubmed/21552260
http://dx.doi.org/10.1038/nsmb.2049