Cargando…
Implications of Molecular Heterogeneity for the Cooperativity of Biological Macromolecules
Cooperativity, a universal property of biological macromolecules, is typically characterized by a Hill slope, which can provide fundamental information about binding sites and interactions. We demonstrate, via simulations and single molecule FRET experiments, that molecular heterogeneity lowers bulk...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109240/ https://www.ncbi.nlm.nih.gov/pubmed/21572445 http://dx.doi.org/10.1038/nsmb.2052 |