Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription

Birt–Hogg–Dubé (BHD) syndrome is an inherited cancer susceptibility disease characterized by skin and kidney tumors, as well as cystic lung disease, which results from loss-of-function mutations in the BHD gene. BHD is also inactivated in a significant fraction of patients with sporadic renal cancer...

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Detalles Bibliográficos
Autores principales: Cash, T P, Gruber, J J, Hartman, T R, Henske, E P, Simon, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109270/
https://www.ncbi.nlm.nih.gov/pubmed/21258407
http://dx.doi.org/10.1038/onc.2010.628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109270/
https://www.ncbi.nlm.nih.gov/pubmed/21258407
http://dx.doi.org/10.1038/onc.2010.628

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