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Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome
Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes phagosomal degradation, and replicates in the macrophage cytosol. The macrophage uses a series of pattern recognition re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109290/ https://www.ncbi.nlm.nih.gov/pubmed/21687410 http://dx.doi.org/10.3389/fmicb.2011.00016 |