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Identification of Residues in the BST-2 TM Domain Important for Antagonism by HIV-1 Vpu Using a Gain-of-Function Approach

The HIV-1 Vpu protein enhances the release of viral particles from the cell-surface in a cell-type specific manner. In the absence of Vpu, nascent virions remain tethered to the cell-surface in restricted cell-types. Recently, the human host factor BST-2/CD317/tetherin was found to be responsible fo...

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Detalles Bibliográficos
Autores principales: Yoshida, Takeshi, Kao, Sandra, Strebel, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109345/
https://www.ncbi.nlm.nih.gov/pubmed/21687426
http://dx.doi.org/10.3389/fmicb.2011.00035