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The Degenerating Substantia Nigra as a Susceptible Region for Gene Transfer-Mediated Inflammation

Parkinson's disease (PD) is characterized by the progressive degeneration of neurons in the substantia nigra pars compacta (SN). The naïve SN is highly susceptible to inflammation. In addition, microglial activation in the degenerating SN displays distinct characteristics that increase the reac...

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Detalles Bibliográficos
Autores principales: Roca, Valeria, Casabona, Juan Cruz, Radice, Pablo, Murta, Verónica, Juan Pitossi, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109520/
https://www.ncbi.nlm.nih.gov/pubmed/21687774
http://dx.doi.org/10.4061/2011/931572