Francisella Tularensis Blue–Gray Phase Variation Involves Structural Modifications of Lipopolysaccharide O-Antigen, Core and Lipid A and Affects Intramacrophage Survival and Vaccine Efficacy

Francisella tularensis is a CDC Category A biological agent and a potential bioterrorist threat. There is no licensed vaccine against tularemia in the United States. A long-standing issue with potential Francisella vaccines is strain phase variation to a gray form that lacks protective capability in...

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Detalles Bibliográficos
Autores principales: Soni, Shilpa, Ernst, Robert K., Muszyński, Artur, Mohapatra, Nrusingh P., Perry, Malcolm B., Vinogradov, Evgeny, Carlson, Russell W., Gunn, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109528/
https://www.ncbi.nlm.nih.gov/pubmed/21687776
http://dx.doi.org/10.3389/fmicb.2010.00129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109528/
https://www.ncbi.nlm.nih.gov/pubmed/21687776
http://dx.doi.org/10.3389/fmicb.2010.00129

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