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α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73

INTRODUCTION: Successful treatment of p53 mutant, triple-negative breast cancers (TNBC) remains a daunting challenge. Doxorubicin (DOXO) and cisplatin (CDDP) are standard-of-care treatments for TNBC, but eventually fail due to acquired drug resistance and toxicity. New treatments for overcoming drug...

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Detalles Bibliográficos
Autores principales: Tiwary, Richa, Yu, Weiping, Sanders, Bob G, Kline, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109563/
https://www.ncbi.nlm.nih.gov/pubmed/21214929
http://dx.doi.org/10.1186/bcr2801