A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation

INTRODUCTION: Estrogen receptor positive breast cancers often have high levels of Mdm2. We investigated if estrogen signaling in such breast cancers occurred through an Mdm2 mediated pathway with subsequent inactivation of p53. METHODS: We examined the effect of long-term 17β-estradiol (E2) treatmen...

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Detalles Bibliográficos
Autores principales: Brekman, Angelika, Singh, Kathryn E, Polotskaia, Alla, Kundu, Nandini, Bargonetti, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109566/
https://www.ncbi.nlm.nih.gov/pubmed/21223569
http://dx.doi.org/10.1186/bcr2804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109566/
https://www.ncbi.nlm.nih.gov/pubmed/21223569
http://dx.doi.org/10.1186/bcr2804

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