Cargando…

Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors via MAPK pathway

INTRODUCTION: In cancer cells, elevated transcription factor-related Brn-3a regulator isolated from brain cDNA (Brn-3b) transcription factor enhances proliferation in vitro and increases tumour growth in vivo whilst conferring drug resistance and migratory potential, whereas reducing Brn-3b slows gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ounzain, Samir, Bowen, Samantha, Patel, Chandrakant, Fujita, Rieko, Heads, Richard J, Budhram-Mahadeo, Vishwanie S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109571/
https://www.ncbi.nlm.nih.gov/pubmed/21241485
http://dx.doi.org/10.1186/bcr2809