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Association of functional polymorphisms in CYP19A1 with aromatase inhibitor associated arthralgia in breast cancer survivors

INTRODUCTION: Aromatase inhibitor-associated arthralgia (AIAA) is a common and often debilitating symptom in breast cancer survivors. Since joint symptoms have been related to estrogen deprivation through the menopausal transition, we hypothesized that genetic polymorphisms in CYP19A1, the final enz...

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Detalles Bibliográficos
Autores principales: Mao, Jun J, Su, H Irene, Feng, Rui, Donelson, Michelle L, Aplenc, Richard, Rebbeck, Timothy R, Stanczyk, Frank, DeMichele, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109575/
https://www.ncbi.nlm.nih.gov/pubmed/21251330
http://dx.doi.org/10.1186/bcr2813