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Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer

INTRODUCTION: Tumors that express estrogen receptor alpha (ERα+) comprise 75% of breast cancers in women. While treatments directed against this receptor have successfully lowered mortality rates, many primary tumors initially or later exhibit resistance. The paucity of murine models of this "l...

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Detalles Bibliográficos
Autores principales: Arendt, Lisa M, Rugowski, Debra E, Grafwallner-Huseth, Tara A, Garcia-Barchino, Maria Jose, Rui, Hallgeir, Schuler, Linda A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109579/
https://www.ncbi.nlm.nih.gov/pubmed/21276249
http://dx.doi.org/10.1186/bcr2819