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Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen

INTRODUCTION: We previously reported an association between tumor-specific 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) expression and a good prognosis in breast cancer. Here, the predictive value of HMG-CoAR expression in relation to tamoxifen response was examined. METHODS: HMG-CoAR...

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Detalles Bibliográficos
Autores principales: Brennan, Donal J, Laursen, Henriette, O'Connor, Darran P, Borgquist, Signe, Uhlen, Mathias, Gallagher, William M, Pontén, Fredrik, Millikan, Robert C, Rydén, Lisa, Jirström, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109580/
https://www.ncbi.nlm.nih.gov/pubmed/21281480
http://dx.doi.org/10.1186/bcr2820