Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry

INTRODUCTION: Selecting women affected with breast cancer who are most likely to carry a germline mutation in BRCA1 and applying the most appropriate test methodology remains challenging for cancer genetics services. We sought to test the value of selecting women for BRCA1 mutation testing on the ba...

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Detalles Bibliográficos
Autores principales: Smith, Letitia D, Tesoriero, Andrea A, Wong, Ee M, Ramus, Susan J, O'Malley, Frances P, Mulligan, Anna Marie, Terry, Mary Beth, Senie, Ruby T, Santella, Regina M, John, Esther M, Andrulis, Irene L, Ozcelik, Hilmi, Daly, Mary B, Godwin, Andrew K, Buys, Saundra S, Fox, Stephen, Goldgar, David E, Giles, Graham G, Hopper, John L, Southey, Melissa C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109582/
https://www.ncbi.nlm.nih.gov/pubmed/21281505
http://dx.doi.org/10.1186/bcr2822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109582/
https://www.ncbi.nlm.nih.gov/pubmed/21281505
http://dx.doi.org/10.1186/bcr2822

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