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Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
INTRODUCTION: Selecting women affected with breast cancer who are most likely to carry a germline mutation in BRCA1 and applying the most appropriate test methodology remains challenging for cancer genetics services. We sought to test the value of selecting women for BRCA1 mutation testing on the ba...
Autores principales: | Smith, Letitia D, Tesoriero, Andrea A, Wong, Ee M, Ramus, Susan J, O'Malley, Frances P, Mulligan, Anna Marie, Terry, Mary Beth, Senie, Ruby T, Santella, Regina M, John, Esther M, Andrulis, Irene L, Ozcelik, Hilmi, Daly, Mary B, Godwin, Andrew K, Buys, Saundra S, Fox, Stephen, Goldgar, David E, Giles, Graham G, Hopper, John L, Southey, Melissa C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109582/ https://www.ncbi.nlm.nih.gov/pubmed/21281505 http://dx.doi.org/10.1186/bcr2822 |
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