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Quantification and clinical relevance of gene amplification at chromosome 17q12-q21 in human epidermal growth factor receptor 2-amplified breast cancers

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers represent a tumor subtype with chromosome 17q rearrangements that lead to frequent gene amplifications. The aim of this study was to quantify the amplification of genes located on chromosome 17q and to analyze the...

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Detalles Bibliográficos
Autores principales: Lamy, Pierre-Jean, Fina, Frédéric, Bascoul-Mollevi, Caroline, Laberenne, Anne-Claire, Martin, Pierre-Marie, Ouafik, L'Houcine, Jacot, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109584/
https://www.ncbi.nlm.nih.gov/pubmed/21288332
http://dx.doi.org/10.1186/bcr2824