Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States

[Image: see text] Amyloid plaques and neurofibrillary tangles simultaneously accumulate in Alzheimer’s disease (AD). It is known that Aβ and tau exist together in the mitochondria; however, the interactions between Aβ oligomers and tau are controversial. Moreover, it is still unclear which specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Yifat, Ma, Buyong, Nussinov, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109766/
https://www.ncbi.nlm.nih.gov/pubmed/21506544
http://dx.doi.org/10.1021/bi200400u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109766/
https://www.ncbi.nlm.nih.gov/pubmed/21506544
http://dx.doi.org/10.1021/bi200400u

Ejemplares similares