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Randomized Trial of Safety and Effectiveness of Chlorproguanil-Dapsone and Lumefantrine-Artemether for Uncomplicated Malaria in Children in The Gambia

BACKGROUND: Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients. This trial was conducted in 2004 to evaluate the safety and effectiveness of CD and comparison with artemether-lumefantrine (AL) under cond...

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Detalles Bibliográficos
Autores principales: Dunyo, Samuel, Sirugo, Giorgio, Sesay, Sanie, Bisseye, Cyrille, Njie, Fanta, Adiamoh, Majidah, Nwakanma, Davis, Diatta, Mathurin, Janha, Ramatoulie, Sisay Joof, Fatou, Temple, Beth, Snell, Paul, Conway, David, Walton, Robert, Cheung, Yin Bun, Milligan, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110183/
https://www.ncbi.nlm.nih.gov/pubmed/21666744
http://dx.doi.org/10.1371/journal.pone.0017371