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Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay

The vast landscape of environmental chemicals has motivated the need for alternative methods to traditional whole-animal bioassays in toxicity testing. Embryonic stem (ES) cells provide an in vitro model of embryonic development and an alternative method for assessing developmental toxicity. Here, w...

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Detalles Bibliográficos
Autores principales: Chandler, Kelly J., Barrier, Marianne, Jeffay, Susan, Nichols, Harriette P., Kleinstreuer, Nicole C., Singh, Amar V., Reif, David M., Sipes, Nisha S., Judson, Richard S., Dix, David J., Kavlock, Robert, Hunter, Edward S., Knudsen, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110185/
https://www.ncbi.nlm.nih.gov/pubmed/21666745
http://dx.doi.org/10.1371/journal.pone.0018540