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Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay
The vast landscape of environmental chemicals has motivated the need for alternative methods to traditional whole-animal bioassays in toxicity testing. Embryonic stem (ES) cells provide an in vitro model of embryonic development and an alternative method for assessing developmental toxicity. Here, w...
Autores principales: | Chandler, Kelly J., Barrier, Marianne, Jeffay, Susan, Nichols, Harriette P., Kleinstreuer, Nicole C., Singh, Amar V., Reif, David M., Sipes, Nisha S., Judson, Richard S., Dix, David J., Kavlock, Robert, Hunter, Edward S., Knudsen, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110185/ https://www.ncbi.nlm.nih.gov/pubmed/21666745 http://dx.doi.org/10.1371/journal.pone.0018540 |
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