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Unexpected Accumulation of ncm(5)U and ncm(5)s(2)U in a trm9 Mutant Suggests an Additional Step in the Synthesis of mcm(5)U and mcm(5)s(2)U
BACKGROUND: Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the maturation process, a subset of the nucleosides are modified. Modifications in the anticodon region often modulate the decoding ability of the tRNA. At position 34, the majori...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110198/ https://www.ncbi.nlm.nih.gov/pubmed/21687733 http://dx.doi.org/10.1371/journal.pone.0020783 |