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3, 3′5 Triiodo L Thyronine Induces Apoptosis in Human Breast Cancer MCF-7cells, Repressing SMP30 Expression through Negative Thyroid Response Elements

BACKGROUND: Thyroid hormones regulate cell proliferation, differentiation as well as apoptosis. However molecular mechanism underlying apoptosis as a result of thyroid hormone signaling is poorly understood. The antiapoptotic role of Senescence Marker Protein-30 (SMP30) has been characterized in res...

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Detalles Bibliográficos
Autores principales: Sar, Pranati, Peter, Rosalima, Rath, Bandita, Mohapatra, Alok Das, Mishra, Sandip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110202/
https://www.ncbi.nlm.nih.gov/pubmed/21687737
http://dx.doi.org/10.1371/journal.pone.0020861