Mineral Composition is Altered by Osteoblast Expression of an Engineered G(s)-Coupled Receptor

Activation of the G(s) G protein–coupled receptor Rs1 in osteoblasts increases bone mineral density by 5- to 15-fold in mice and recapitulates histologic aspects of fibrous dysplasia of the bone. However, the effects of constitutive G(s) signaling on bone tissue quality are not known. The goal of th...

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Detalles Bibliográficos
Autores principales: Kazakia, G. J., Speer, D., Shanbhag, S., Majumdar, S., Conklin, B. R., Nissenson, R. A., Hsiao, E. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110278/
https://www.ncbi.nlm.nih.gov/pubmed/21526395
http://dx.doi.org/10.1007/s00223-011-9487-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110278/
https://www.ncbi.nlm.nih.gov/pubmed/21526395
http://dx.doi.org/10.1007/s00223-011-9487-z

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