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Mineral Composition is Altered by Osteoblast Expression of an Engineered G(s)-Coupled Receptor
Activation of the G(s) G protein–coupled receptor Rs1 in osteoblasts increases bone mineral density by 5- to 15-fold in mice and recapitulates histologic aspects of fibrous dysplasia of the bone. However, the effects of constitutive G(s) signaling on bone tissue quality are not known. The goal of th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110278/ https://www.ncbi.nlm.nih.gov/pubmed/21526395 http://dx.doi.org/10.1007/s00223-011-9487-z |