Cargando…
Disease Model Distortion in Association Studies
Most findings from genome-wide association studies (GWAS) are consistent with a simple disease model at a single nucleotide polymorphism, in which each additional copy of the risk allele increases risk by the same multiplicative factor, in contrast to dominance or interaction effects. As others have...
Autores principales: | Vukcevic, Damjan, Hechter, Eliana, Spencer, Chris, Donnelly, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110308/ https://www.ncbi.nlm.nih.gov/pubmed/21416505 http://dx.doi.org/10.1002/gepi.20576 |
Ejemplares similares
-
Quantifying the Underestimation of Relative Risks from Genome-Wide Association Studies
por: Spencer, Chris, et al.
Publicado: (2011) -
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
por: Giambartolomei, Claudia, et al.
Publicado: (2014) -
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
por: Cortes, Adrian, et al.
Publicado: (2017) -
link-ancestors: fast simulation of local ancestry with tree sequence software
por: Tsambos, Georgia, et al.
Publicado: (2023) -
The influence of sighing respirations on infant lung function measured using multiple breath washout gas mixing techniques
por: Vukcevic, Damjan, et al.
Publicado: (2015)