The Over-expression of the β2 Catalytic Subunit of the Proteasome Decreases Homologous Recombination and Impairs DNA Double-Strand Break Repair in Human Cells

By a human cDNA library screening, we have previously identified two sequences coding two different catalytic subunits of the proteasome which increase homologous recombination (HR) when overexpressed in the yeast Saccharomyces cerevisiae. Here, we investigated the effect of proteasome on spontaneou...

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Detalles Bibliográficos
Autores principales: Collavoli, Anita, Comelli, Laura, Cervelli, Tiziana, Galli, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110333/
https://www.ncbi.nlm.nih.gov/pubmed/21660142
http://dx.doi.org/10.1155/2011/757960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110333/
https://www.ncbi.nlm.nih.gov/pubmed/21660142
http://dx.doi.org/10.1155/2011/757960

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