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Cryptococcus neoformans Requires a Functional Glycolytic Pathway for Disease but Not Persistence in the Host

Cryptococcus neoformans is an important fungal pathogen of immunocompromised individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the immunocompetent. During initial infection, C. neoformans colonizes the airspaces of the lungs, resulting in pneumonia, and subseq...

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Detalles Bibliográficos
Autores principales: Price, Michael S., Betancourt-Quiroz, Marisol, Price, Jennifer L., Toffaletti, Dena L., Vora, Haily, Hu, Guanggan, Kronstad, James W., Perfect, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110414/
https://www.ncbi.nlm.nih.gov/pubmed/21652778
http://dx.doi.org/10.1128/mBio.00103-11