Cargando…

Cryptococcus neoformans Requires a Functional Glycolytic Pathway for Disease but Not Persistence in the Host

Cryptococcus neoformans is an important fungal pathogen of immunocompromised individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the immunocompetent. During initial infection, C. neoformans colonizes the airspaces of the lungs, resulting in pneumonia, and subseq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Price, Michael S., Betancourt-Quiroz, Marisol, Price, Jennifer L., Toffaletti, Dena L., Vora, Haily, Hu, Guanggan, Kronstad, James W., Perfect, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110414/ https://www.ncbi.nlm.nih.gov/pubmed/21652778 http://dx.doi.org/10.1128/mBio.00103-11

Ejemplares similares

Pleiotropic Effects of Deubiquitinating Enzyme Ubp5 on Growth and Pathogenesis of Cryptococcus neoformans
por: Fang, Wei, et al.
Publicado: (2012)

Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii
por: Holcomb, Zachary E., et al.
Publicado: (2022)

The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus Cryptococcus neoformans
por: Caza, Mélissa, et al.
Publicado: (2016)

Identification of Genes from the Fungal Pathogen Cryptococcus neoformans Related to Transmigration into the Central Nervous System
por: Tseng, Hsiang-Kuang, et al.
Publicado: (2012)

The cAMP/Protein Kinase A Pathway and Virulence in Cryptococcus neoformans
por: Kronstad, James W., et al.
Publicado: (2011)

The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis
por: Chen, Yuan, et al.
Publicado: (2014)

Transcriptional Regulation by Protein Kinase A in Cryptococcus neoformans
por: Hu, Guanggan, et al.
Publicado: (2007)

Proteasome inhibition as a therapeutic target for the fungal pathogen Cryptococcus neoformans
por: Caza, Mélissa, et al.
Publicado: (2023)

Landscape of gene expression variation of natural isolates of Cryptococcus neoformans in response to biologically relevant stresses
por: Yu, Chen-Hsin, et al.
Publicado: (2019)

The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans
por: Horianopoulos, Linda C., et al.
Publicado: (2020)

Comparative hybridization reveals extensive genome variation in the AIDS-associated pathogen Cryptococcus neoformans
por: Hu, Guanggan, et al.
Publicado: (2008)

Inositol Metabolism Regulates Capsule Structure and Virulence in the Human Pathogen Cryptococcus neoformans
por: Wang, Yina, et al.
Publicado: (2021)

Involvement of Mrs3/4 in Mitochondrial Iron Transport and Metabolism in Cryptococcus neoformans
por: Choi, Yoojeong, et al.
Publicado: (2020)

Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients
por: Hu, Guanggan, et al.
Publicado: (2011)

The Spectrum of Interactions between Cryptococcus neoformans and Bacteria
por: Mayer, François L., et al.
Publicado: (2019)

The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans
por: Attarian, Rodgoun, et al.
Publicado: (2018)

Dnj1 Promotes Virulence in Cryptococcus neoformans by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress
por: Horianopoulos, Linda C., et al.
Publicado: (2021)

The monothiol glutaredoxin Grx4 influences thermotolerance, cell wall integrity, and Mpk1 signaling in Cryptococcus neoformans
por: Hu, Guanggan, et al.
Publicado: (2021)

HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans
por: Jung, Won Hee, et al.
Publicado: (2010)

Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans
por: So, Yee-Seul, et al.
Publicado: (2019)

Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam
por: Thanh, Lam Tuan, et al.
Publicado: (2020)

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans
por: Caza, Mélissa, et al.
Publicado: (2018)

The cAMP/Protein Kinase A Pathway Regulates Virulence and Adaptation to Host Conditions in Cryptococcus neoformans
por: Caza, Mélissa, et al.
Publicado: (2019)

Erratum for Attarian et al., “The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans”
por: Attarian, Rodgoun, et al.
Publicado: (2019)

Cryptococcus neoformans Is Resistant to Surfactant Protein A Mediated Host Defense Mechanisms
por: Giles, Steven S., et al.
Publicado: (2007)

Networks of fibers and factors: regulation of capsule formation in Cryptococcus neoformans
por: Ding, Hao, et al.
Publicado: (2016)

Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model
por: Colombo, Ana Caroline, et al.
Publicado: (2019)

Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans
por: Jung, Won Hee, et al.
Publicado: (2008)

Melanization in Cryptococcus neoformans Requires Complex Regulation
por: Cordero, Radames J. B., et al.
Publicado: (2020)

Mechanisms of Cryptococcus neoformans-Mediated Host Damage
por: Casadevall, Arturo, et al.
Publicado: (2018)

Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
por: Gaylord, Elizabeth A., et al.
Publicado: (2020)

The Role of Host Gender in the Pathogenesis of Cryptococcus neoformans Infections
por: McClelland, Erin E., et al.
Publicado: (2013)

Iron Regulation of the Major Virulence Factors in the AIDS-Associated Pathogen Cryptococcus neoformans
por: Jung, Won Hee, et al.
Publicado: (2006)

Comparison of Cryptococcus gattii/neoformans Species Complex to Related Genera (Papiliotrema and Naganishia) Reveal Variances in Virulence Associated Factors and Antifungal Susceptibility
por: Oliveira, Lana Sarita de Souza, et al.
Publicado: (2021)

Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System
por: Yu, Chen-Hsin, et al.
Publicado: (2021)

UDP-Glucuronic Acid Transport Is Required for Virulence of Cryptococcus neoformans
por: Li, Lucy X., et al.
Publicado: (2018)

A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans
por: Mayer, François L., et al.
Publicado: (2018)

Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection
por: Campuzano, Althea, et al.
Publicado: (2017)

Correction: Iron Regulation of the Major Virulence Factors in the AIDS-Associated Pathogen Cryptococcus neoformans
por: Jung, Won Hee, et al.
Publicado: (2016)

Disarming Fungal Pathogens: Bacillus safensis Inhibits Virulence Factor Production and Biofilm Formation by Cryptococcus neoformans and Candida albicans
por: Mayer, François L., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2kntm4vjjt28bb64vlf1apsvih