Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma

PURPOSE: We recently demonstrated that molecular therapy using aminoglycosides can overcome the underlying genetic defect in two zebrafish models of ocular coloboma and showed abnormal cell death to be a key feature associated with the optic fissure closure defects. In further studies to identify mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gregory-Evans, Cheryl Y., Moosajee, Mariya, Shan, Xianghong, Gregory-Evans, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110494/
https://www.ncbi.nlm.nih.gov/pubmed/21677791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110494/
https://www.ncbi.nlm.nih.gov/pubmed/21677791

Ejemplares similares