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Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival

Despite exhibiting oncogenic events, patient's leukemia cells are responsive and dependent on signals from their malignant bone marrow (BM) microenvironment, which modulate their survival, cell cycle progression, trafficking and resistance to chemotherapy. Identification of the signaling pathwa...

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Detalles Bibliográficos
Autores principales: Maia, Sara, Pelletier, Marc, Ding, Jixin, Hsu, Yen-Ming, Sallan, Stephen E., Rao, Sambasiva P., Nadler, Lee M., Cardoso, Angelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110793/
https://www.ncbi.nlm.nih.gov/pubmed/21687682
http://dx.doi.org/10.1371/journal.pone.0020787