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A Latent Model for Prioritization of SNPs for Functional Studies

One difficult question facing researchers is how to prioritize SNPs detected from genetic association studies for functional studies. Often a list of the top M SNPs is determined based on solely the p-value from an association analysis, where M is determined by financial/time constraints. For many s...

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Detalles Bibliográficos
Autores principales: Fridley, Brooke L., Iversen, Ed, Tsai, Ya-Yu, Jenkins, Gregory D., Goode, Ellen L., Sellers, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110798/
https://www.ncbi.nlm.nih.gov/pubmed/21687685
http://dx.doi.org/10.1371/journal.pone.0020764