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Rapid Turnover of 2-LTR HIV-1 DNA during Early Stage of Highly Active Antiretroviral Therapy

BACKGROUND: Despite prolonged treatment with highly active antiretroviral therapy (HAART), the infectious HIV-1 continues to replicate and resides latently in the resting memory CD4+ T lymphocytes, which blocks the eradication of HIV-1. The viral persistence of HIV-1 is mainly caused by its proviral...

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Detalles Bibliográficos
Autores principales: Zhu, Weijun, Jiao, Yanmei, Lei, Rongyue, Hua, Wei, Wang, Rui, Ji, Yunxia, Liu, Zhiying, Wei, Feili, Zhang, Tong, Shi, Xuanlin, Wu, Hao, Zhang, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110824/
https://www.ncbi.nlm.nih.gov/pubmed/21687638
http://dx.doi.org/10.1371/journal.pone.0021081