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Role of IL-1α in Cisplatin-Induced Acute Renal Failure in Mice

BACKGROUND/AIMS: For unknown reasons, caspase-1 -/- mice, protected against cisplatin-induced acute renal failure (ARF), are deficient in interleukin (IL)-1α. We thus asked whether IL-1α deficiency underlies the mechanism of protection against cisplatin-induced ARF in these mice. METHODS: Cisplatin...

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Detalles Bibliográficos
Autores principales: Lee, Jay-Wook, Nam, Woo-Jin, Han, Min-Jee, Shin, Jung-Ho, Kim, Jin-Gun, Kim, Su-Hyun, Kim, Hye-Ryoun, Oh, Dong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110851/
https://www.ncbi.nlm.nih.gov/pubmed/21716595
http://dx.doi.org/10.3904/kjim.2011.26.2.187